Here are some studies and commentary on this:
Soft drinks, fructose consumption, and the risk of gout in men: prospective cohort studyHyon K Choi, associate professor of medicine1, Gary Curhan, associate professor of medicine2
BMJ, doi: 10.1136/bmj.39449.819271.BE, (Published 31 January 2008)
http://www.bmj.com/cgi/content/short/bmj.39449.819271.BEv1 ".... Other major contributors to fructose intake such as total
fruit juice or fructose rich fruits (apples and oranges) were also associated with a higher risk of gout (P values for trend <0.05).
Conclusions: Prospective data suggest that consumption of sugar sweetened soft drinks and fructose is strongly associated with an increased risk of gout in men. Furthermore, fructose rich fruits and fruit juices may also increase the risk. Diet soft drinks were not associated with the risk of gout."
Fructose is a coronary risk factorTuesday, August 04, 2009
http://heartscanblog.blogspot.com/2009/08/fructose-is-coronary-risk-factor.htmlAs discussed in a previous Heart Scan Blog post, Say Goodbye to Fructose, a carefully-conducted University of California study demonstrated that, compared to glucose, fructose induces:
1) Four-fold greater intra-abdominal fat accumulation
2) 13.9% increase in LDL cholesterol, doubled Apoprotein B
3) 44.9% increase in small LDL, 3-fold more than glucose
4) Increased postprandial triglycerides 99.2%.
Other studies have shown that fructose:
--Increases uric acid--No longer is red meat the cause for increased uric acid; fructose has taken its place. Uric acid may act as an independent coronary risk factor and increases high blood pressure and kidney disease.
--Induces insulin resistance, the situation that creates diabetes
--Increases glycation (fructose linked to proteins) and protein cross-linking, processes that underlie atherosclerosis, liver disease, and cataracts.
Make no mistake: Fructose is a powerful coronary risk factor.
There is no doubt whatsoever that a diet rich in fructose from
fruit drinks, honey, raisins and other dried fruit like cranberries, sucrose (table sugar), and high-fructose corn syrup is a high-risk path to heart disease.
Also note that many foods labeled "heart healthy" because of low-fat, low saturated fat, addition of sterol esters, or fiber, also contain fructose sources, especially high-fructose corn syrup.
Calorie Restricted Monkeys Part IITuesday, July 14, 2009 at 4:10PM
http://www.paleonu.com/"...why don’t the monkeys get CAD, despite our successful efforts to give them the metabolic syndrome that correlates so closely with CAD risk in humans?
My shoot-from-the-hip speculation is that Homo Sapiens, during two million years of evolution since H.Habilis, lost what little tolerance for excess fructose we started with at the same time we acquired our metabolic preference for exploiting the fat stores of other mammals and became more tolerant of saturated fat than fructose.
Sugar is just more poisonous to humans, and that is why you have to try so hard to give CAD to monkeys, even if you are stimulating inflammation with gobs of linoleic acid. CAD may depend on not tolerating fructose. That would explain a lot and we should keep that in mind when reading animal studies.
So among the Neolithic agents, excess industrial oils are probably bad for most mammals, but sugar may be peculiarly bad for humans. Step one of PaNu stays step one."
And here is the discussion continued from
http://www.rawpaleoforum.com/general-discussion/for-first-time-chimps-seen-making-weapons-for-hunting!/30/:
PaleoPhil wrote: "You could make that same sort of excuse re: the nonhydrogenated fat study--it used cottonseed oil, so I could say I don't use plant oils and only heat grassfed suet at low temps, writing the study off as useless in the same manner."
Not at all useless. It establishes that cooking is a harmful process.
If you can say that the cottonseed oil study establishes that cooking anything is harmful, then I can say the refined fructose studies establish that all sugars are harmful.
And claiming that "only" lightly cooking suet would be OK is meaningless.
If you can say that, then I can say that claiming that "only" fruit fructose is OK is meaningless.
Once one has to accept(as all have to do eventually) that cooking harms food in numerous ways, it becomes increasingly impossible to argue convincingly that cooking is a beneficial process.At best, one is forced on the defensive, to make a vague unsupoorted claim that cooking "doesn't really do that much harm".
Same can be said for fructose and more. Since there are studies connecting actual fruit fructose to gout and heart disease, the evidence is actually more direct re: fruit fructose than cooking suet. You seem to have much lower standards of evidence for your hypotheses than you do for those you disagree with.
Fruit juice is a heavily processed food, involving added artificial vitamin C, heated/pasteurised to abnormally high temperatures to kill off potential bacteria and soft drinks are hardlt healthy carbs. Similiarly, dried fruits contain artificial levels of sulphur and other preservatives, hardly healthy or natural.
OK, we agree on fruit juice and dried fruits. Now, did it ever occur to you--why is fruit juice and dried fruit seriously unhealthy but beef blood and dried beef is not--or do you think beef blood and low-heat, homemade jerky are as unhealthy as fruit juice and dried fruit? If you do, please provide evidence.
Cranberries have been shown to be beneficial in fighting bacterial infections in the urinary system and have been shown to protect against cancer and kidney stones:-
As Carnivore, and I think Lex, said, some foods can have short term medicinial effects that are beneficial without necessarily being healthy as long run staple foods.
As for gout, that is routinely linked by scientists to consumption of (cooked) meats with fruit actually helping reduce gout symptoms(gout is linked to purines present in protein-foods especially organ-meats):-
http://www.ncbi.nlm.nih.gov/pubmed/15014182
That study says that dairy products reduce risk of gout. Surely you don't agree with that.
The presentation at the following link claims that "low fat dairy products may be protective":
http://www.docstoc.com/docs/2984210/GOUT-TREATMENT-Part-3. Surely you don't agree with that either. There are a lot of bogus studies and recommendations when it comes to gout.
http://www.wisegeek.com/what-are-some-foods-that-cause-gout.htm
This article contradicts the study and says that dairy products increase the risk of gout. I've researched gout before and found the same contradictions. There is no agreement on which foods cause it. I also know someone with gout and the purine-free diet didn't do her much good. I'm not convinced that purines are the whole answer.
Even an advocate of moderately-restricted purine diets questions the value of total purine elimination, suggesting there is at least an additional factor at work:
Gout, Diet, and the Insulin Resistance Syndrome
http://www.jrheum.com/subscribers/02/07/1350.html"... A rigid purine restricted diet is of dubious therapeutic value and can rarely be sustained for long", so says a gout expert, professor A. G. Fam in "gout, diet, and the insulin resistance syndrome.
...Although high protein diets contain large quantities of purines and are associated with an increased rate of endogenous purine production, such diets often increase urinary urate excretion, and may even lower serum urate levels19,54. ....
CONCLUSION
While dietary restriction of purines has long been superseded by more effective urate-lowering drugs, recent data suggest that dietary measures may play a much greater role in the treatment of metabolic disorders commonly associated with gout: obesity, IRS, and dyslipidemia."
Plus, of course, the scientific concensus, nowadays, is that fruit and veg consumption PROTECTS against heart-disease:-
A) consensus is no guarantee of correctness (the current consensus is that so-called "unbalanced, extreme elimination" diets like RPD are nonsense and that you are therefore outside the pale, remember--just read the PaNu doctor's comments about RPD if you don't believe me--he attacks several of your views)
B) it depends on what they're replacing--when fruit and veg replace grains and dairy, they do protect against heart disease; if raw, pasture-fed meats and organs replaced the fruit and cooked veg, I think they would probably find even better protection against heart disease
It is far more likely that the scientists simply recognised that their data conflicted somewhat with the findings of 1000s of other studies proving helath benefits for fruits, so that they made a qualifying statement so as not to look too foolish,
They want to keep their jobs, so they genuflect to the dietary dogma, which I don't blame them for. I just wouldn't make the mistake of claiming it's a scientific practice to disregard the results of your own study without logical explanation or investigation.
Similiarly, there are now so many definitive studies done on the great harm of heat-created toxins on human health that it is now scientifically implausible to argue that well-cooked foods(especially well-cooked animal foods) are remotely healthy for humans - which means, of course, that rawists have already won half the battle already, on a scientific basis.
Many scientists may recognize problems with deep fat frying and other high-temp cooking methods, but raw diets are still regarded as dangerous quackery in most of the scientific and medical communities. RPD is a minority view among raw diets and a minority view among Paleo diets. Even the PaNu doctor whose diet is nearly raw and very similar to ours (aside from dairy) lambasted much of the views associated with the RPD. If he responded that way imagine how conventional doctors and scientists will respond when they find out about RPD.
As GS has pointed out from his own experience, wild fruits are available all year round in quantity as a staple in the tropics, so the same must have applied in Palaeo times(in those equatorial regions).
The vast majority of human beings do not descend from people from Southeast Asia, including me, so the fruits avialable in that area are irrelevant to me. Africa and Eurasia did not have the same flora and even the flora of SE Asia has been greatly manipulated over thousands of years of human intervention. Since you seem fond of scientitic consensus, the scientific consensus re: the habitat of early hominids is that it was Savannah land, not tropical. Even the minority Aquatic Ape view does not support a tropical habitat. The ancestors of Europeans did not live in tropics during at least the last half million years.